In addition to diet and exercise, to improve glycemic control in adult patients with type 2 diabetes. Not for type 1 diabetes or diabetic ketoacidosis.
Tradjenta is the ONLY single-strength DPP-4i* with no dose adjustment, regardless of renal function2
When TRADJENTA is used in combination with an insulin secretagogue (eg, sulfonylurea [SU]) or insulin, a lower dose of the insulin secretagogue or insulin may be required to reduce the risk of hypoglycemia.
TRADJENTA DOSING AND ADMINISTRATION
The recommended dose of TRADJENTA is 5 mg once daily
TRADJENTA can be taken with or without food
TRADJENTA is not primarily eliminated via the kidney
- 5% eliminated via the kidney
- 80% excreted via the bile and gut within 4 days of dosing
References: 1. Bailey RA, Wang Y, Zhu V, Rupnow MF. Chronic kidney disease in US adults with type 2 diabetes: an updated national estimate of prevalence based on Kidney Disease: Improving Global Outcomes (KDIGO) staging. BMC Res Notes. 2014;7:415. 2. The National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF KDOQI). “How to Classify CKD.” kidney.org. https://www.kidney.org/professionals/explore-your-knowledge/how-to-classify-ckd. Accessed on September 18, 2018.